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[42] The American College of Obstetricians and Gynecologists states that while they can be used in the first trimester other options may be preferred

10.1016/j.bbcan.2019.188314 6 BaiJ.ZhangY.TangC.HouY.AiX.ChenX.et al (2021)

While there is evidence that growth hormone (GH) secretagogues like ipamorelin can increase lean body mass and decrease fat mass in seniors [11], long-term research shows that elevated GH levels increase disease risks and decrease life expectancy by accelerating the aging process [12]

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Are there better early interventions