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17.2.2.4 Clinical Presentation Solitary neurofibromas present as relatively non-tender masses in the skin or subcutaneous tissue

Los pacientes pueden notar cambios iniciales en el apetito y el peso dentro de las primeras semanas , pero la prdida de peso contina durante al menos 72 semanas (18 meses) de tratamiento, segn los estudios SURMOUNT

In some patients with PMOS, the ovaries may not contain these enlarged follicles