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Kidney Medicine, 3(2), pp.282285

Do not take an additional dose

As confirmatory secondary endpoints, the team assessed whether participants attained at least 10%, 15%, and 20% bodyweight reduction till week 68 and reported any physical function outcomes, which included absolute body weight, BMI, waist circumference, blood pressure, glucose homeostasis changes, and glycaemic status

Deficiency leads to methylmalonic acid accumulation, which can cause neurological damage over time

Individuals with genetic variants in the GLP1R gene (such as rs6923761) or GIPR gene (rs1800437) may show differential receptor sensitivity, meaning a combination approach can activate multiple pathways more effectively than monotherapy alone