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Ponesimod compared with teriflunomide in patients with relapsing multiple sclerosis in the active-comparator phase 3 OPTIMUM study: A randomized clinical trial
These experiments indicated a pH optimum of pH 7.58 in the presence of 400 M MSA and 2 mM NAD +
I would likely have experienced neurological damage with that treatment
On the basis of type of the study, the heterogeneity between the subgroups and within each subgroup was quite high, i.e., 98% among observational studies and 97% among RCT's and a leave-one-out sensitivity analysis showed no significant change in heterogeneity by omitting any study as shown in Fig
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