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Clinical transparency, 15%: Published claims, testing notes, and clear directions improved scores

Metabololipidomics For oxylipin analysis, 200 L culture supernatants were transferred to 2 mL of ice-cold methanol containing 10 L of deuterium-labeled internal standards (200 nM d8-5S-HETE, d4-LTB 4 , d5-LXA 4 , d5-RvD 2 , d4-PGE 2 and 10 M d8-AA

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68 Additionally, large-leaf yellow tea polysaccharides remodel the gut microbiota by reducing BSH-producing genera and increasing taurine-metabolizing genera, thereby altering colonic bile acid composition, increasing levels of conjugated bile acids and non-12OH bile acids, inhibiting ileal FXR receptors and hepatic bile acid reabsorption, promoting bile acid synthesis and fecal excretion, and subsequently inhibiting NAFLD progression

This means the FDA does not review these drugs for safety, efficacy, or quality before they reach patients