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Gene expression profiling of photoaged skin treated with GHK-Cu reveals normalization of over 70% of UV-dysregulated genes, with particularly strong effects on genes involved in matrix synthesis, inflammatory responses, and oxidative stress defense

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5b) 23,45

Based on section 1848(c)(2)(C)(i) of the Act, which requires the Secretary to determine a number of work relative value units for the service or group of services based on the relative resources incorporating physician time and intensity required in furnishing the service, including global surgical services, we continue to believe standalone E/M services should be exempt from the efficiency adjustment as detailed in the CY 2026 PFS proposed rule (90 FR 32593 through 32597)

[Google Scholar] CNN Health (2018)