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Data availability The RNA-seq data generated in this study are available on the National Center for Biotechnology Information (NCBI) database with SRA accession code: PRJNA1212571

Therefore, in contrast to most conventional antibiotics that perturb the homeostasis of normal microbiota, the antivirulence approach intends to target and inhibit the molecules and structures vital for bacteria to inflict disease [89]

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N-acetyl-p-aminophenol appeared to be the most satisfying compound, which was introduced for limited use in 1893, and for wide unrestricted use after 1950s

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