[DOI] [PubMed] [Google Scholar] 68.Thornalley P.J., McLellan A.C., Lo T.W.C., Benn J., Snksen P.H
It is produced independently by the organism and is present in almost all of our body cells, with the exception of red blood cells
LRRK2 is recruited to the mitochondrial outer membrane by mitochondria-anchored Rab29 (also called Rab7L1) ( RAB29 is also a risk gene of PD identified in PARK16 loci from several GWASs (Satake et al., 2009), and in addition to mitochondria Rab29 is also distributed at trans-Golgi network, lysosomes, and autophagic vesicles to regulate membrane trafficking, lysosome homeostasis, and axonal transport of autophagosomes with LRRK2 (Liu et al., 2018
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It helps to relax the blood vessels and increase blood flow