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Primary care relevance: Providers will soon be able to prescribe the higher dose, but should counsel patients about the potential for more gastrointestinal side effects and dysaesthesia

MHRA guidance emphasises the importance of monitoring patients during the initial months of Mounjaro therapy, particularly during dose escalation

Smaller portions spread throughout the day are much easier to tolerate, and planning ahead for balanced meals and snacks can help maintain energy and nutrient intake, says Zimmermann

The first biguanide to be tested on humans in the XX century was metformin

Warning signs include profound muscle weakness, severe fatigue, or abnormal heart rhythms