DPP4 and the RAAS are linked genetically and are associated with the risk of SARS-CoV-2 infection and possibly severity of COVID-19, particularly in patients with diabetes mellitus 76
In vivo investigation demonstrated that GLP-1 receptor agonism with exenatide was able to reduce CSF secretion and ICP by at least 45% [16]
Transition probabilities are modeled as clinically informed first-order Markov processes depending on age, sex, education, race, health conditions, body mass index (BMI) and functional status
Compounded peptides have not undergone this process, but they can be prescribed by a physician for an individual patient based on their professional judgment
Also, it was unclear why the control patients didn't fill their GLP-1 prescriptions, leaving open the possibility of confounding