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Glutathione-mediated redox regulation in Cryptococcus neoformans impacts virulence

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Using the C-terminal MRPm6 epitope 1511-1520, retained in all chimeras, we checked by microscopy and Western blot that the proteins were correctly addressed at the plasma membrane level (Fig

The released ROS activate the ion channel TRPM2 in macrophages, promoting calcium influx, thereby eliciting an immune response

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