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Additionally, the evidence base for efficacy and safety specifically in BED populations remains limited
Additionally, animal studies have found that exposure to glucagon-like peptide-1 receptor agonists in pregnancy resulted in adverse outcomes for offspring that included decreased fetal growth, skeletal and visceral anomalies, and embryonic death
It is composed of two domains, one transmembrane (TMD) domain that binds the N-terminal region of GLP-1 and the extracellular (ECD) that binds the C-terminal helix of GLP-1
The FDA permits so-called compounding, or customized production, when there is a shortage of the official versions of FDA-approved medications
PMID: 19008308
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