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(PubMed) Lodge JK, Youn HD, Handelman GJ, et al

The N-hexanoic (C-terminal) and 6-aminohexanoic amide (N-terminal) modifications introduced during the lead-optimization phase of the Harding laboratorys Ang IV-analog program were specifically designed to increase hydrophobicity, decrease hydrogen bonding, and improve metabolic stability against the proteases that degrade native angiotensin IV

Grizzle WE, Xu X, Zhang S, Stockard CR, Liu C, Yu S, Wang J, Mountz JD, Zhang HG

Encapsulation of Nile red or fluorescein to PLGA nanoparticles To PLGA solution in acetone (1.0 mL, 25 mg/mL) either Nile red or PLGA-fluorescein was dissolved (0.2% w/w) and then the resulting solution was added drop wise into stirring water (5.0 mL)