crohn's and semaglutide Weight Loss Medications & IBD Ozempic and Crohn's Disease: Safety,

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Second, we took plasma samples only up to 5 h postprandially, however, to comprehensively investigate second-meal effects, sampling for longer periods and/or longer-term supplementation of fiber to increase colonic fermentation may be required

In addition, Tsai et al

A 2025 randomized pragmatic trial found that semaglutide delivered a 15% greater reduction in HbA1c than hormone-based comparators, underscoring the need to adjust insulin or secretagogue dosing to reduce hypoglycemia risk

Whitten, D.L