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The problem is straightforward: more weight loss means more physiological stress, and more physiological stress means a stronger trigger for hair shedding

Commonly Reported Nausea reported in 2433% of subjects depending on dose, generally transient and improving with continued use

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Phillips IR, Shephard EA

Abstract The discovery of intrinsically disordered proteins (IDPs) (and, therefore, the establishment of the field of protein intrinsic disorder) was initially driven by low-resolution techniques, which overturned the established lock-and-key paradigm of structural biology by showing that some proteins exist as a dynamic conformational ensemble rather than a single fixed structure