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They need a few practical guardrails consistent hydration, a protein anchor, smaller-but-regular eating, and a realistic expectation that the first weeks of dose changes can feel off. This guide shows the simplest levers that reliably help

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Ethanol is also a substrate for the CYP enzymes responsible for NAPQI generation and competes with paracetamol for CYP2E1, reducing the amount of NAPQI being produced [Citation43]