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A 2025 study in Diabetes, Obesity, and Metabolism found that participants reported improvements in food-related thoughts, feelings of fullness, and overall healthier eating behaviors

Only in people with existing mild cognitive impairment or Alzheimer's disease, where meta-analyses show a modest benefit at 120 to 240 mg daily for 12 to 24 weeks

Distribution channel: In 2025, hospital pharmacies occupied the largest market share of 44.3%, with the fastest growth projected to be the online pharmacies with a CAGR of 17.1% between 2026 and 2035

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9 NO is generated by an enzyme named NO synthase, whose only physiological substrate is the semiessential amino acid L-arginine