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Fluoxetine works by blocking the reabsorption of serotonin in the brain, thereby increasing serotonin availability at neuronal synapses

In turn, reduced inflammation may lead to a lower risk of various life-threatening diseases

Other limitations include the fact that the in vitro granuloma model used is not an exact replication of in vivo granulomas which have a more complex and dynamic environment containing other cells like fibroblasts, collagen matrix, and other white blood cells

Efficient drug delivery by novel cell-penetrating peptide derived from Midkine, with two heparin binding sites braced by a length-specific helix

PMID 12167058