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[23] concluded that allicin effectively ameliorated vascular and cardiac remodelling induced by hypertension through inhibition of the CaMKII/NF-B signalling pathway, reduction in serum levels of IL-1, IL-6, and TNF-, improvement in calcium homeostasis in cardiomyocytes, and downregulation of the NLRP3 inflammasome

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Mika, A., Minibayeva, F., Beckett, R

Cardiovascular Benefits: Reduces major adverse cardiovascular events by 26% in patients with type 2 diabetes and established cardiovascular disease (NEJM SUSTAIN-6 trial, 2016)