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Moreover, uracil, n-oleoylethanolamine, asymmetric (ADMA) and symmetric (SDMA) dimethylarginines (protein degradation residues), palmitoylglycerol (active metabolite) and pseudouridine (nucleotide metabolism) were depleted in T4 only, whereas -muricholic acid (bile acid) was depleted in T5

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DNA HYPERMETHYLATION AT THE PROMOTER REGION OF KEAP1 GENE Epigenetic alterations also facilitate NRF2 stabilization