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If confirmed, this could eventually be due to small differences in bioavailability, distribution or elimination of the peptide-antibody fusion compared to conventional mAbs

Indeed, when the mice were treated with antioxidants in addition to the drug, the therapeutic effects were diminished and their metastatic tumor burden increased

PMID 15521026

10.1038/s41591-024-03412-w [DOI] [PubMed] [Google Scholar] ZEPBOUND (2024)

A systematic review and doseresponse metaanalysis of RCTs that investigated the effects of GT on obesity found that GT supplementation was associated with a reduction in body weight (WMD: 1.78 kg, 95% CI: 2.80 to 0.75, p = 0.001) and body mass index (WMD: 0.65 kg/m 2 , 95% CI: 1.04 to 0.25, p = 0.001)