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Clinical trials show patients who discontinue treatment regain approximately two-thirds of lost weight over the following year, while A1C levels typically rise as the medication's metabolic effects cease

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Long-Term Considerations and Chronic Use Because obesity is a chronic condition requiring ongoing management, orforglipron will likely be used for years or even decades by many patients

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Improved Gut Health: Supports the repair of gastrointestinal tissues for better digestion and overall health