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The compound is a quinolinium-class structure (5-amino-1-methylquinolinium) developed as a membrane-permeable selective inhibitor of the nicotinamide N-methyltransferase enzyme

For instance, Tat mediates astrocyte senescence and the production of ROS and pro-inflammatory cytokines, while gp120 and methamphetamine induce apoptosis [165, 166]

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