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Phase 2 Published 2023 The New England Journal of Medicine The most-cited medical journal in the world Jastreboff et al., 2023 338 adults with obesity, randomized to placebo or one of four Retatrutide doses (1, 4, 8, 12 mg weekly)

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Regeneron leans into obesity with Phase II data Additional dose ranging and longer term data necessary to address safety questions Regenerons Phase II data for its myostatin and activin A inhibitors is the latest to demonstrate the lean mass lost from GLP-1 therapy and the ability of these mechanisms to improve the quality of weight loss from combination therapy

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