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This characteristic makes KPV a uniquely accessible tool for intestinal inflammation research compared to most research peptides, which are degraded before reaching gut tissue

Licensed pharmacological options such as orlistat and semaglutide (Wegovy, per NICE TA875) may be appropriate for eligible individuals

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Therefore, we suggest that our case report may contribute to the formation of standardised desensitisation protocol in vitamin B12 allergy

Adverse effects observed in trials to date include: Gastrointestinal symptoms nausea, vomiting, diarrhoea, and constipation (common with GLP-1 receptor agonists) Reduced appetite and weight loss , which may be excessive in some individuals Elevated heart rate , a concern noted with glucagon receptor agonism As with other incretin-based therapies, there is also a class-level signal for acute pancreatitis and gallbladder disease (including cholelithiasis and cholecystitis)