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However, high-dose or long-term use can lead to osteoporosis by increasing the expression of M-CSF and RANKL while inhibiting osteoblast-related signaling pathways such as Wnt/-catenin

Generic Name: Vitamins B1 + B6 + B12 (Thiamine + Pyridoxine + Cyanocobalamin)

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Primary objectives for pharmaceutical weight loss should focus on optimizing diet composition and nutrient intake in addition to managing side effects. Here, the study emphasized adhering to general guidance on higher protein intake calculated for g/kg for lean mass preservationpresenting meal replacement shakes as a relatively low-calorie, low-fat source of protein that can be supplemented with vitamins and minerals to help fill dietary gaps

10.1016/j.molmed.2011.10.001 Trends Mol