Vitamin B 6 , folate, and vitamin B 12 regulate the amount of circulating homocysteine (see Figure 1 above), and a deficiency of any of these B vitamins can lead to hyperhomocysteinemia, a condition treated through B vitamin supplementation
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It also serves to keep the hemoglobin iron in the ferrous state by reducing peroxides that undergo a reaction in which they extract an electron from ferrous iron, converting it to ferric iron, which impairs hemoglobin function