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Other factors contributing to leadership in the region include increased awareness about the co-morbid diseases associated with obesity, greater physician involvement, vigorous scientific research, and pharmaceutical investment in oral GLP-1 drugs, incretin-based, and multi-agonist drugs

Moreover, ROS facilitates tumor invasion and metastasis by enhancing the migration of cancer cells, often through the regulation of matrix metalloproteinases and epithelial-mesenchymal transition

S2A, C, E)