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Noteworthily, we observed that long-acting GLP-1 RAs offer more pronounced benefits, potentially due to their sustained pharmacological action, suggesting a dependency on pharmacokinetic profiles for maximal therapeutic impact

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Real-time PCR data showed that the major isoforms expressed in MIN6 cells are Adcy 6 and 9, suggesting that low intracellular Ca 2+ levels block inhibition of Adcys

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