Research from the American Diabetes Association shows that GLP-1 medications can increase the risk of muscle loss, and patients are often advised to consume more protein to preserve muscle
This slow-release mechanism is what allows Wegovy to be a once-weekly treatment
GLP-1 side effects should be discussed with a doctor when nausea, constipation, vomiting, reflux, fatigue, dizziness, abdominal pain, dehydration, or poor intake interferes with daily life, prevents the patient from eating enough protein or drinking enough fluid, worsens after a dose increase, persists for more than a short adjustment period, or feels severe or unusual
These pleiotropic effects include the reduction of BW and BP, the improvement of lipid metabolism and a spectrum of cardioprotective effects
References Cheema AY, Munir M, Mandala A, Aslam F, Acharya U