B vitamins, especially vitamin B12, B6, thiamine (B1), riboflavin (B2) and niacin (B3), play key roles in energy metabolism
Sleep apnea is a manifestation of the metabolic syndrome
Its a real disruption for a real group of people who were using this thing carefully and feeling results and its a non-event for people who were treating it like a supplement you throw in a smoothie
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And you know, do you run the risk of having a false negative trial with those low event rates if the bleeding outcome was studied separately