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Results Effect of colistin on mitochondrial membrane potential and oxygen consumption rate in freshly isolated mitochondria To assess the mitochondrial toxicity of colistin, freshly isolated mitochondria were incubated for one hour with 1 M colistin, and then the quenching of the Rho123 fluorescent signal was monitored over time

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A phylogenetically tree showed that GpoA present a higher homology with genes found in bacteria that belong to the Phylum Bacillota (before known as Firmicutes ), mainly in the genus Streptococcus (Fig S1)

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