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The severity of bloating often varies between individuals and may be dose-dependent, typically being more pronounced during the initial weeks of treatment or following dose escalations

To rescue the Al 2 O 3 NPs induced mitochondria dysfunction, disruption of small molecular metabolites of HBE were profiled using metabolomics analysis, which facilitates identification of potential antagonizer or supplement against nanoparticle-involved damages

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Evaluation method Results were assessed using three methods: (1) SALT (Severity of Alopecia Tool) scoring, (2) blinded dermatologist evaluation of before/after photographs, and (3) AI-assisted assessment using ChatGPT