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Disruption of its function has been identified in several neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and prion diseases, as well as in amyotrophic lateral sclerosis (ALS)

PMID: 34345678 Martinez, A., et al

Key Takeaways Heart rate signal is not a prominent feature of the 5-amino-1MQ preclinical literature

If CagriSema receives regulatory approval, it would likely become the standard of care for obesity treatment, potentially displacing semaglutide and tirzepatide as first-line options