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Several study limitations warrant acknowledgment, including controlled laboratory conditions that may not reflect field environments, short-term exposure effects without addressing potential resistance development, and lack of evaluation of effects on beneficial insects and soil microorganisms

100% with 30% reduction), normalization of ALT in 79% of those who had it elevated, and improvements in non-invasive markers of fibrosis 22

Please refer to the full 2020 ADA Standards of Care for additional details and recommendations regarding intensification of therapy beyond dual antihyperglycemic therapy

Vitamin C is required for the hydroxylation step that converts proline to hydroxyproline

Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Mller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kssl J, et al