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We need longer-term real-world data comparing maintenance of weight loss at one year, two years or longer across strategies, including adherence and cost-effectiveness analyses

Clinical trials like SURMOUNT-1 showed average weight loss of 15 to 22.5 percent of body weight over 72 weeks depending on dose

Metformin is a prescription medication approved for the treatment of type 2 diabetes that helps to lower blood sugar levels when diet and exercise alone are not enough to move the needle

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IGF-1 is the main anabolic mediator of growth hormone