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In this state, molecular motion is minimal and degradation pathways are effectively paused

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The redox state of GSH/GSSG in plasma is controlled by multiple processes, includ- ing the synthesis of GSH from its constitutive amino acids, cyclic oxidation and reduction involving GSH peroxidase and GSSG reductase, protein S-glutathionylation, transport of GSH into plasma, and degradation of GSH and GSSG by -glutamyltranspeptidase [31,42]