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At the end of the study, 33% of the Pycnogenol subjects reported the complete disappearance of leg heaviness and 63% did not feel any swelling

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The 24-week trials allowed for assessment of several long-term safety considerations

Importantly, in vivo studies in Severe Combined Immunodeficiency (SCID) mice showed that the nanocarrier accumulates effectively at tumor sites and exhibits minimal systemic toxicity, as evidenced by favorable histological outcomes