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Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes

Exendin-4 preserves blood-brain barrier integrity via glucagon-like peptide 1 receptor/activated protein kinase-dependent nuclear factor-kappa B/matrix metalloproteinase-9 inhibition after subarachnoid hemorrhage in rat

These studies have generally demonstrated positive therapeutic outcomes, but translation to clinical applications requires careful consideration of species differences and experimental limitations

Funding support for the study came, in part, from Novo Nordisk

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