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Description

Amylin signaling is closely connected to nutrient handling, gastric motility, and postprandial metabolic responses, which makes cagrilintide relevant in experimental models examining glycemic control and endocrine-metabolic communication [1]

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FIGURE 12 3.6 Comparative estimation of free energy of binding between SR18GLP-1R and GLP-1GLP-1R complexes To further understand the energetic contribution of the crucial residues of GLP-1R toward SR18 compared to GLP-1, the MD trajectories were subjected to gmx_MMPBSA calculations

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