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For instance, patients using liraglutide (Saxenda), which is specifically approved for weight loss, typically experience average weight reductions of approximately 57% of their initial body weight after one year

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A possible explanation for the similar effects on weight of both GIP agonism and antagonism is the potential desensitisation of GIP receptors by GIP agonists exposure [57]

For people with type 2 diabetes, the STEP-2 trial showed average weight loss of around 9.6% on the 2.4mg dose, roughly 64% of the result in people without diabetes 4