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Se calcula con la siguiente frmula: HOMA-IR = glucosa srica en ayuno (mg/dl) x insulina en ayuno (mUI/L)/405 (Tabla 2) 15

Studies show an average weight loss of 10 to 15 percent of body weight

These obese mice also showed activation of microglia and astrocytes and significant immunoreactivity of neuroinflammatory and apoptosis markers, such as TNF-, COX-2, and Caspase-3, in addition to lower expression of neurogenesis and synaptic plasticity markers, such as NeuN, KI-67, CREB-p, and BDNF