If that methionine residue plays a role in receptor binding or biological activity, oxidation can reduce or eliminate the peptide effect entirely
Theyre frustrated and looking for something, anything, that might work
(7) Tianqi Liu, Ying Liu, Xiaoyu Zhao, Liguo Zhang, Wei Wang, De Bai, Ya Liao, Zhenyuan Wang, Mi Wang, Jiaheng Zhang, Thermodynamically stable ionic liquid microemulsions pioneer pathways for topical delivery and peptide application, Bioactive Materials, Volume 32, 2024, Pages 502-513 (8) Malinda KM, Sidhu GS, Mani H, Banaudha K, Maheshwari RK, Goldstein AL, Kleinman HK
BPC-157 or TB-500 reconstitution Healing peptides like BPC-157 and TB-500 use much smaller doses (measured in micrograms, not milligrams) and typically come in smaller vials (5 mg is common)
doi:10.1016/0196-9781(95)02027-6