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doi: 10.2147/OAJSM.S91657

Accumulating evidence has demonstrated that chemicals targeting DRD2 or Nrf2 increase GSH levels in the brain and confer neuroprotective effects 44,45,46

These medications work by slowing digestion, reducing appetite, and improving blood sugar controlall of which can be incredibly beneficial for women over 50

Ozempic (semaglutide) slows gastric emptying and reduces gastrointestinal motility as part of its mechanism of action, which can decrease bowel movement frequency and cause constipation in 1-10% of users

According to the Phase 2 trial published in the New England Journal of Medicine , retatrutide achieved weight reductions up to 24.2% at 48 weeks , with projections nearing or exceeding 25% at full duration (Coskun et al., 2023)