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179 S100B levels are elevated in the CSF or serum of patients with MDD, 180 which suggests that S100B is a potential diagnostic biomarker for depressive episodes associated with MDD

Only conjugated bilirubin can react with the diazonium ion, because the conformation of unconjugated bilirubin shields or protects the central methylene [CH 2 ] group within the molecule, which is what the diazo dye interacts with