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Obese patients are more likely to see knee arthritis due to stress on the joints caused by their weight, which leads to cartilage breakdown and inflammation

Results vary based on: Starting weight Metabolic factors Consistency with treatment Most are mild and temporary: Nausea (usually subsides in weeks) Constipation Headaches Severe side effects are rare but include pancreatitis or gallbladder issues

Patients requiring chloramphenicol therapy should have their hematological parameters monitored closely if continuing this medication

They also emphasize that additional randomized clinical trials involving broader populations and longer follow-up periods will be important for confirming these findings and evaluating their generalizability