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J Clin Invest (2000) 105:45968

People with digestive conditions, such as irritable bowel syndrome (IBS), may find that their symptoms worsen when they take a fiber supplement

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Safe alternatives include metformin, SGLT2 inhibitors (empagliflozin, dapagliflozin), DPP-4 inhibitors (sitagliptin, linagliptin), and exenatide immediate-release or lixisenatide, which do not carry thyroid cancer warnings