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Reportaron, en el ao 2008, el caso de una paciente afectada por SLH que present un melanoma en boca

NRAS-mutated melanoma cell lines (SB2 and SK-Mel-2) migrate efficiently toward HGF but this process is completely inhibited by PHA-665752, and treatment with 50100 nM PHA-665752 inhibited phosphorylation of Akt

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