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Clin Ther (2006) 28(1):5572

As curli protein is one of the major components of the bacterial extracellular matrix, it was shown to accelerate fibrilization by cross-seeding and aggregation of -synuclein and -amyloid ( in vitro neuroblastoma cell line and in vivo A53T -synuclein over-expressing C

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Patients with certain genetic profiles show higher sensitivity to GLP-1 effects, meaning they reach therapeutic results at lower doses and suffer more severe side effects if over-dosed

Long-acting agents demonstrate superior efficacy in reducing nonfatal and ischaemic stroke risk, with relative risk reductions ranging from 15% to 39% across major trials