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While some people try to buy compounded tirzepatide online and compounded semaglutide to save money, its risky because the dosing might not be accurate, and the medication might not be made under proper safety standards
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The medication is not suitable for patients with a personal or family history of medullary thyroid carcinoma (MTC), MEN 2 syndrome (multiple endocrine neoplasia type 2 syndrome), or pancreatitis
Their multifaceted mechanismsincluding weight loss, improved glycemic control, anti-inflammatory effects, and lipid profile enhancementcontribute to substantial cardiovascular benefits
This effect is also observed after specific activation of GLP-1R in the NAc and most likely those receptors located on medium spiny neurons that express the dopamine-D1 receptors or dopamine-D2 receptors (Zhang et al., 2020)
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